The relative sensitivity of serum lipase versus amylase for radiological image-positive pancreatitis

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Combined serum amylase and lipase determinations for diagnosis of suspected acute pancreatitis.

Serum amylase and lipase measurements are often used to diagnose acute pancreatitis. This study addresses the question of whether it is advantageous to order serum amylase and lipase tests simultaneously. We evaluated performance of the two tests separately and in combination through a retrospective study of patients for whom both amylase and lipase determinations were ordered. Initial analysis...

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A critical evaluation of serum lipase and amylase as diagnostic tests for acute pancreatitis

Laboratory testing of serum amylase and/or lipase levels are central to the diagnosis of acute pancreatitis (AP) as these tests are quick, cheap, reliable and perhaps the only objective criteria available at the bedside at the time of initial presentation. It is important to understand the physiology and biochemistry of these tests in order to get a clear grasp of their diagnostic utility. Lipa...

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Persistence of increased amylase and lipase concentrations in acute pancreatitis.

We question the variations in serum concentrations of lipase and amylase during acute pancreatitis reported by Loft and Lu (1). In the caption for their Figure 3, the authors stated that the graphs of the two enzymes in a patient with acute pancreatitis demonstrated “characteristic changes with time.” Serum concentrations of both enzymes peaked on the fourth day after onset and still had not de...

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Serum lipase activity is increased in disease states other than acute pancreatitis: amylase revisited.

For more than 50 years, total serum amylase activity has been the biochemical test most commonly used to confirm the clinical diagnosis of acute pancreatitis. Serum amylase activity has been hoisted onto this pedestal by default, because until recently it has been the only reproducible and rapid diagnostic assay available in clinically emergent settings. As a result of our longstanding dependen...

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Low Serum Pancreatic Amylase and Lipase Values Are Simple and Useful Predictors to Diagnose Chronic Pancreatitis

Background/Aims This study aimed to evaluate the diagnostic role of low serum amylase and lipase values in the detection of chronic pancreatitis. Methods Patients underwent endoscopic retrograde cholangiopancreatography and were diagnosed with non-calcific chronic pancreatitis (NCCP; n=99) and calcific chronic pancreatitis (CCP; n=112). Patient serum amylase and lipase values were compared wi...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2007

ISSN: 1364-8535

DOI: 10.1186/cc5562